Useful information

Ginura from 100 diseases

In recent years, not only people are actively moving around the world. Both plants and their products travel. The arisen interest in the traditional medicine of Asian countries has brought to our market products from many interesting plants, which most, with the exception of, perhaps, narrowly specialized botanists, have never heard of.

Pueraria, guarana, codonopsis, ashwagandha have become almost familiar and familiar to many. But few have heard about ginura (in Latin transcription) or ginura (in English transcription), although someone is already trying to grow it on a windowsill or in a winter garden.

Ginura prostrate

Ginura prostrate (Gynura procumbens) is a small plant from the Aster family, 1-3 m high. The stems are fleshy, and the leaves are ovoid-elliptical or lanceolate, in my opinion, somewhat reminiscent of dahlia leaves. Sometimes in literature it is found under the names Gynura sarmentosa and Cacalia sarmentosawhich are synonymous.

The leaves of the plant are traditionally used for food in Thailand and Malaysia. In Malay this plant is called Sambung Nyawa, which means "life extension", and in Chinese it is called Bai Bing Cao, which means "100 diseases", and it is used very widely for a variety of ailments. In Japan, ginuru is called "Okinawa spinach", and there, as you know, there are a lot of centenarians.

Ginura prostrate

In other countries, the healing effect of the plant has also long been known: in Indonesia, it is used to treat kidneys, and in Vietnam, for fever. Current active research in many countries has provided extensive scientific evidence for the therapeutic potential of this ginura.

The beneficial properties of ginura are explained by the presence of biologically active compounds in this plant, such as flavonoids and glycosides.

Based on the needs of modern civilization, plants useful in cardiovascular diseases always come to the fore - hypertension is a key risk factor for the development of certain cardiovascular diseases, including coronary heart disease and stroke - and ginura has shown in experiments a high antihypertensive and cardioprotective activity ...

To date, it has been proven that the use of this plant leads to a significant decrease in systolic and mean arterial pressure, as well as a significant decrease in heart rate. True, experiments, albeit very deep and meticulous, to find out which enzyme is blocked and which is activated, were carried out on rats. The enzyme angiotensin leads to the formation of a peptide hormone with a strong vasoconstrictor effect, and ginura drugs inhibit its action. Another possible mechanism of the extract's vasodilating action is inhibition of extracellular Ca2 + influx. Thus, prostrate ginura potentially serves as an antihypertensive agent with cardioprotective activity due to its ability to act on various mechanisms.

Ginura prostrate

The second big problem in our society is diabetes. The leaves of this plant are commonly used to treat diabetes in traditional medicine, and their hypoglycemic effects have been reported in animal studies. At the same time, it was precisely the regulatory activity that was emphasized, that is, the effect was present only in sick animals, and the sugar level in healthy animals did not change. Currently, researchers are arguing whether the plant extract affects the intensity of pancreatic insulin secretion. But recently, the majority is still inclined to believe that the effect is not associated with insulinotropic activity, but is due to a different mechanism of action. Other avenues in research have focused on glucose uptake activity. They showed that the consumption of glucose by muscles increases precisely in rats with diabetes, and the extract G. procumbens stimulated an increase in the utilization of glucose in the liver and a decrease in the production of endogenous glucose.

In addition to directly treating diabetes, research on ginura prostrate has also explored its potential in treating infertility, which is one of the complications of diabetes. It turned out that taking the extract significantly increases the number of spermatozoa, their motility, and reduces the percentage of their death. It was also shown that G. procumbens has aphrodisiac properties. Ginura can improve the fertility of infertile diabetic men, especially by increasing sperm count, quality and motility.

Ginura common has long been used for traditional cancer treatments in Asian countries, such as leukemia, uterine cancer, and breast cancer. This provoked extensive scientific research into its anticancer activity. In most cases, the experiments did not go beyond the laboratory, but in many cases they confirmed the people's experience. It was found that short-term (10 weeks) treatment with an ethanol extract of the plant suppressed the progression of nitroquinoline-1-oxide-induced tongue carcinogenesis during the initiation phase. A longer period (26 weeks) of administration has been shown to result in a strong suppression of oral carcinogenesis. Ethanol extract proved to be effective against the carcinogenic effect of 7,12-dimethylbenz (a) anthracene on the liver and on the osteosarcoma cell line. Ethanol extract has recently been shown to G. procumbens has some potential to prevent colon cancer and has also demonstrated its potential in the prevention of breast cancer. It has been shown to effectively suppress the proliferation of breast cancer and mammary epithelial cells. In addition, further studies have shown that treatment G. procumbens able to reduce the incidence of tumor in test animals.

Ginura prostrate

Most studies have concluded more about the preventive effect of the plant. Patients with cancer often use herbal medicine as complementary and alternative medicine when undergoing chemotherapy. In this regard, studies were conducted on the combined use of ginura and chemotherapy drugs. In studies by Japanese scientists, the combination of ginura extract with doxorubicin or 5-fluorouracil led to a strong synergistic effect against breast and colon cancer cells, but when combined with ginura extract with cisplatin, it turned out that they act as antagonists. This shows that the simultaneous use of G. procumbens with different chemotherapy drugs can lead to different treatment efficacy. So the researchers still have a lot of work to do.

The antimicrobial activity of ginura is worthy of separate studies. Research shows that ginura extract is active against Plasmodium malaria strains Plasmodium falciparum 3D7 and Plasmodium berghei NK65. In addition, it has been demonstrated that an ethanol extract of parts of aerial plants exhibits virucidal and anti-replicative activity of herpes simplex HSV-1 and HSV-2. This was confirmed in a clinical study in patients with recurrent lip herpes who were treated with herbal extract gels. G. procumbens... Antibacterial activity has been found against gram-positive and gram-negative bacteria such as Bacillus cereus, Pseudomonas aeruginosa, Vibrio parahaemolyticus and Salmonella typhi... Antifungal activity was noted against the causative agent of thrush Candida albicans and mold Aspergillus niger... The results of these studies provided evidence of the validity of the traditional use of ginura for malaria and herpes.

The antioxidant activity of the extracts was assessed using the DPPH assay to measure its ability to scavenge free radicals. In a comparative study, ethanol extract G. procumbens showed a very high percentage of DPPH inhibition (52.81%). Further study of antioxidant activity using a number of different analyzes showed that ginura exhibits significant antioxidant activity. Research has shown that root extract has the highest antioxidant activity compared to other parts of the plant. Thus, in numerous and varied experiments, it has been established that ginura is a powerful source of natural antioxidants, probably due to its high content of phenols.

Found that ginura has a gastroprotective effect in gastric ulcer, with a decrease in submucosal edema. This discovery has intrigued researchers to further investigate the protective effect of the plant's preparations. Later, a protective effect on the skin was found when exposed to ultraviolet light.

researchers are particularly interested in the hepatoprotective effect, as it has been shown to attenuate ethanol-induced lipid accumulation in the liver.

In Thai traditional medicine G. procumbens commonly used to treat inflammation. Topical application of ethanol extract to the wounds of the test animals showed significant signs of skin healing, a smaller scar width and a significantly faster healing rate compared to the saline control group). In addition, histological analysis also showed that there are fewer inflammatory cells and more collagen in the granulation tissue of the wound.

Depending on the dose used in the experiment, ginura acted either as an immunostimulant or as an immunosuppressant. Hence, anti-inflammatory and immunomodulatory activity G. procumbens can be used to treat inflammatory diseases or conditions in which the immune system is involved.

Among the existing patents mentioning this plant, most of them refer to traditional Chinese medicines for the treatment of various diseases, including uterine cancer, cervical spondylosis and chronic skin diseases. In addition, it has also been used as an ingredient in special diets for patients with cardiovascular disease and liver disease.

Ginura tea

In the food industry, ginura is included in foods such as tea, kimchi (a Korean vegetable dish), coffee powder, chocolate, candy, and chewing gum. There is also information about the application G. procumbens in personal care and cosmetic products, including hand wash solution, hand sanitizer, mouth spray, face masks, and skin care creams. These patents have demonstrated high commercial value G. procumbens and the variety of its applications in a number of industries.

Considering that for centuries the plant has been food, it is probably worth paying attention to it as a potential product for maintaining, if not eternal, but long-term health.

Ginura prostrateVitamin remedy from ginura

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